Although all investment advisers registered with the SEC are subject to the same legal and regulatory regime, advisers that employ quantitative (quant) investment strategies face certain unique challenges. A recent ACA Compliance Group (ACA) program examined compliance considerations for a quant adviser’s investment methodology, model governance and testing; compliance oversight and control; trade and coding errors; backtesting; and information security. The program featured Michael Abbriano, senior principal consultant at ACA, and Michael Pappacena, partner at ACA Aponix. This article highlights the key points from the presentation. For more on quant investing, see “An Introduction to Quantitative Investing: Dispelling Myths and Misconceptions (Part One of Three)” (Aug. 9, 2018).